Enhances mitochondrial energy and recovery
In macrophages isolated from mouse myocardium after infarction and in bone marrow-derived macrophages (BMDMs) exposed to ACs in vitro, the concentration of intracellular fatty acids and mitochondrial oxygen consumption upregulated -oxidation and OXPHOS, leading to the generation of NAD+ and promoting the activation of SIRT1 (a sirtuin) that targets PPAR activity and genes related to mitochondrial biogenesis [71, 72]
Bulletin of experimental biology and medicine , 154 (3), 403410
doi: 10.1016/j.freeradbiomed.2011.05.004 134
Oral intake of enzymatically decomposed AP collagen peptides improves skin moisture and ceramide and natural moisturizing factor contents in the stratum corneum
Ultimately, the application of senescence-targeting therapies could revolutionize the way we approach aging and aging-related diseases, offering a pathway to healthier, more productive lives as we age