In renal tubular epithelial cells treated with calcium oxalate (CaOx) to induce kidney stone formation, CHAC1 expression increases alongside a decreased GSH level, reduced GPX4 activity, increased iron and MDA content and elevated ROS and lipid peroxidation
The markers that we were most interested in testing were related to Aspergillus colonization, yeast colonization, mitochondrial status, and glutathione status
[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Tobias GC, Gomes JLP, Fernandes LG, Voltarelli VA, de Almeida NR, Jannig PR, de Souza RWA, Negro CE, Oliveira EM, Chammas R, Alves CRR, Brum PC
Sensitivity analyses including MR Egger regression, weighted median, weighted mode (both weighted and simple), maximum likelihood, and RAPS yielded consistent results, thereby reinforcing our causal inferences
All five of them
Diabetologia 29:4654 Knop FK, Vilsbll T, Hjberg PV et al (2007) Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state