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This finding was first well established in women who are heterozygous for hypoxanthine phosphoribosyltransferase deficiency, and it has also been observed in several women heterozygous for severely deficient G6PD variants

It is ubiquitous in living systems

It stimulates immune response while balancing excessive inflammation and is a great option for chronic fevers, bronchitis, and tuberculosis-like conditions

Because the intranasal forms have lower absorption than the IM dosage form, intranasal B12 forms are administered once weekly

It is contraindicated in pregnant or breastfeeding women due to the risks it could pose to the infant