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Evidence from clinical and animal studies has demonstrated that GLP-1RAs might improve myocardial metabolism and reduce the incidence of AF [7]

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Since mTOR is located downstream of AMPK and mTOR has been well reported to regulate muscle growth and metabolism 42,43 as well as the eIF4EBP3L as a gatekeeper of mTOR in muscle growth 44 , we next examined the effect of mTOR pathway by measuring the levels of mTOR and eif4ebp3l in the LMNA mutant transgenic fish with or without drug treatment

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K., Kochanek, S