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MAIT cell activation and dynamics associated with COVID-19 disease severity

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Significantly, sleep deprivation disrupts the circadian rhythm of estrogen secretion and causes a variety of endocrine disorders, leading to a decline in estrogen levels (15)

The first line of defense against superoxide is the presence of a specific member of the family of metalloenzymes called superoxide dismutases (SODs), MnSOD or SOD2, specifically located in the mitochondrial matrix, which catalyzes the dismutation of superoxide anion into H 2 O 2 as shown in Figure 2