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In the high glucose cultured HRMECs model, intervention with berberine can upregulate the expression of Nrf2, HO-1, GPX4, and FSP1 while inhibiting ACSL4 (221)

Kojic acid lightens surface pigmentation, while glutathione brightens the skin from within for overall whitening

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16 The average IVD height was calculated by averaging the measurements obtained from the anterior, middle, and posterior portions of the IVD and dividing that average by the average of adjacent vertebral body heights

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