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Notable innovations include: SGLT2 inhibitors improving both glycemic control and kidney health

Concentrations are in M and velocities in M/hr

doi: 10.1016/j.jad.2023.04.113

Liraglutide (Saxenda) was FDA-approved in 2014 for weight-management in adults with overweight and obesity

937 SEMA5A-IT1 in peripheral blood circulating small extracellular vesicles is an important regulatory molecule protecting against myocardial I/R injury, providing a target for the prevention and treatment of tissue I/R injury

As awareness grows that GLP-1induced weight loss can include significant muscle loss, patents have begun claiming combinations with myostatin and ActRII pathway modulators [14, 15], while scientific papers examine the mechanisms and clinical implications of body composition changes during incretin therapy [13, 23]