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Uddin TM, Chakraborty AJ, Khusro A, et al

Endoplasmic reticulum stress The endoplasmic reticulum is an important organ within the cell that is involved in regulating the synthesis, folding, and modification of intracellular proteins

In clinical research, that effect is often reflected through body weight reduction and waist circumference change over defined protocol windows, and those endpoints are exactly what the phase 2 cagrilintide trial reported