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Although the identity of the PPM transporter for pantothenate remains unknown, it is also a candidate drug target given the reliance on pantothenate uptake for parasite survival

A recombinant human glucagon-like peptide (GLP)-1albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis

Per a 2024 Marketdata report, tirzepatide is on track to become a best-selling drug, with projected sales hitting $36.5 billion by 2025

For gene knockdown study, IPEC-J2 cells were infected with shLacz cloned adenovirus (AdshLacz) or shGPX4 cloned adenovirus (AdshGPX4) or shSELS cloned adenovirus (AdshSELS) at MOI of 50 for 48 h