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That kind of discount, once volumes build, could significantly reduce GLP-1 spend for employer and retiree plans

A commenter noted that in some cases CMS did not use ASP data reported to CMS to set Medicare payment limits and recommended the agency to rely on reported ASP data whenever available, given that manufacturers submit this information quarterly in accordance with statutory requirements established by the Consolidated Appropriations Act (CAA), 2021

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JANUMET is contraindicated in patients with severe renal impairment [see Contraindications (4) and Warnings and Precautions (5.1)]

All figures were created with biorender.com

Regulatory and Technical Hurdles Federal regulators like the FDA-CVM and the USDA require companies to prove that peptide-based treatments are safe and effective before selling them as drugs