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Despite these side effects, the overall incidence of adverse events leading to discontinuation of treatment was relatively low

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A isolated from the brain tissue of Alzheimers disease patients are found in complex with copper, and purified A binds copper in vitro 57

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The laccase activity was measured by adding 180 l of reaction mixture (100 mM citratephosphate buffer pH 4.0 and 1 mM ABTS) by using a Multidrop robot (Multidrop Combi, Thermo Scientific)