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A combo could drive greater weight loss and also better GI (gastrointestinal) tolerability via lower tirzepatide combo dosing

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3 Unlike other negative emotions (eg, fear or sadness) that are associated with withdrawal or flight, anger promotes approach and anger as well as arousal of the autonomic nervous system, 4 with increases in heart rate, muscle tone, adrenal release, and characteristic facial expressions of a clenched jaw and furrowed brow