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What the Research Shows on Semaglutide and Tirzepatide The relationship between GLP-1 medications and skin laxity is well-documented in the aesthetic-medicine literature, which increasingly frames GLP-1-associated skin changes as a legitimate concern requiring proactive management

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Trials in NAFLD often show the same pattern: biochemical improvement within a few months and inconsistent imaging changes that may require three to six months or more

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