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The European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) reviewed the evidence in 2024 and concluded there is no causal link between GLP-1 receptor agonists and increased suicide risk, though continued monitoring is advised

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glp-1 has been shown to act autonomously in the germline [12], and based on the mechanism of Notch signaling, we presume lag-1 function autonomously too

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