Email us your question at [email protected]
Traditionally GLP-1(9-36) was considered inactive, however more recent studies indicate that GLP-1(9-36) can contribute to inhibiting glucagon secretion by inhibiting voltage-gated calcium channels through a GPCR mechanism, an effect which reduces the number of glucagon containing vesicles that are available for exocytosis, thereby contributing the the decrease in glucagon secretion (Figure 1)(Zheng et al, 2024)
Clinically, semaglutide did not slow cognitive decline to a statistically meaningful degree compared with placebo
It enrolled 17,605 participants, average age 61.6 years, who were obese or overweight (BMI average = 33 kg/m2) withou t diabetes but with prior heart attack, stroke or peripheral artery disease
When to Reconsider Phentermine, and Safer Alternatives If you've been prescribed phentermine for weight loss, discuss with your physician whether discontinuing it in favor of a single GLP-1 agent makes sense for your cardiovascular profile and weight loss goals
Fueling your body with good nutrition supports: reduced inflammation improved wound healing steadier energy preservation of lean tissue Proper post-operative nutrition does not cause weight gain
