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Patients with sulfa or sulfite sensitivity warrant extra care, and a thorough allergy history covering not just the active ingredient but preservatives and additives in the formulation should precede any infusion
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[DOI] [PubMed] [Google Scholar] 69.van Barneveld AA, van den Hamer CJA
Best Practices to Minimize Local Irritation (Research Context Only) General laboratory handling considerations may include: Rotating administration sites Avoiding repeated use of the exact same location Allowing alcohol to fully dry before administration Injecting slowly Ensuring complete dissolution before drawing solution Avoiding overly concentrated reconstitution ratios Avoiding overly shallow (intradermal) placement and ensuring material is delivered into the intended subcutaneous layer when applicable Very superficial placement into the dermal layer may increase the likelihood of visible welts or raised bumps, as fluid deposited intradermally tends to remain localized and elevated rather than dispersing within subcutaneous tissue
Always follow the product instructions or work with a practitioner who can guide you based on your specific situation
