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Likewise, in AD mouse model, scutellarein was reported to inhibit TRPV3 channel activity, accompanied by reduced, accompanied by reduced neural hyperexcitability, lower serum IgE levels, and decreased expression of proinflammatory cytokines including IL-1, TNF-, IL-4, IL-6, and CXCL15 (Wang Y
Aug 16 2021;11(8):e053019
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