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Monitor geriatric patients receiving rosuvastatin for the increased risk of myopathy [see Warnings and Precautions (5.1)]

Technical challenges include the transient nature of metabolites and contamination-prone technologies such as Liquid Chromatography-Mass Spectrometry (LC-MS) (Zhou et al., 2012

The levels of ALC in people and rodents with depression are significantly reduced

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Adequate stomach acid production and enzyme activity promote proper digestion, potentially reducing the volume and duration of gastric contents available for reflux