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Semaglutide improved Kansas City Cardiomyopathy Questionnaire (KCCQ) scores by 7 to 8 points more than placebo, produced 13% weight loss, improved six-minute walk distance by approximately 20 meters, and reduced C-reactive protein (a marker of inflammation) by about 40%

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Pharmaceutical research, 16(9), 14121416 Svensson, J., Lall, S., Dickson, S

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63 The accumulated NAPQI depletes GSH in the endoplasmic reticulum to induce an oxidationreduction imbalance, which initiates the phosphorylation of eukaryotic initiation factor 2 (eIF2) to activate ATF6 and CHOP, eventually resulting in hepatocyte apoptosis (Figure 2)

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