Alcohol is a triple threat: it contains histamine (especially wine and beer), it inhibits DAO activity, and it increases intestinal permeability (allowing more histamine to enter circulation)
The production of GLP-1 happens after eating
However, side effects like nausea, dizziness, or gastrointestinal discomfort may also become more likely as the dose increases
Focus on fruits and vegetables that are high in fiber Eat small high protein meals as digestion is slowed down while on this medication Avoid foods high in fat as they take longer to digest Limit alcohol intake as this medication can lower blood pressure Drink at least 32oz of water a day to avoid constipation Do Not Take This Medication If: You have a personal or family history of medullary thyroid carcinoma (Thyroid Cancer) Multiple Endocrine Neoplasia syndrome type 2 You are pregnant or plan to become pregnant while taking this medicine You are diabetic and/or taking any medications related to lowering your blood sugar levels without speaking with your endocrinologist
Fan Y-Y, Davidson LA, Callaway ES et al (2015) A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells
Unlike prescription GLP-1 medications, dietary supplements focus on nutritional ingredients traditionally used to support the bodys natural metabolic responses