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GLP-1Rs are expressed in some T-cells

Once food passes through the gastrointestinal tract (GI), taste receptors, along with mechanosensors and chemoreceptors within the GI tract, transmit information via afferent branches of the vagus nerve and hormonal signaling (e.g., GLP-1, GIP, PYY, insulin, among others) (46)

AHIP and payer CEOs have pointed to these benefits in pledging to adopt ePA standards ( [42] ) ( [14] )

Given the high disease burden of NASH and limited therapeutic options currently available, the FDA has proposed an accelerated pathway for drug approval

Ueki K, Sasako T, Okazaki Y, Kato M, Okahata S, Katsuyama H, et al

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