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The HSV-1 genome can be modified through genetic engineering in two main ways: first, by reducing infectivity and toxicity to normal cells via limited replication and assembly, altered protein-virus receptor binding, and minimized immune evasion

CMS did not, contrary to the commenter's understanding, propose defining or deeming them to be primary care providers. Additionally, the primary care services provided by physician assistants, nurse practitioners, and clinical nurse specialists have been used in the Shared Savings Program assignment methodology ( 425.402) since the inception of the program

CBSAs are composed of entire counties