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HCG exists as multiple glycoforms, including regular HCG, hyperglycosylated HCG, free subunit, core fragments, and nicked variants, each differing in carbohydrate structures and biological roles

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Metabolomics-based research may further reveal valuable biomarkers for therapy monitoring, as the reprogramming of ammonium metabolism in prostate cancer generates a range of intermediate metabolites, such as polyamines, citrate, and various amino acids, as well as key metabolic enzymes, which hold promise as indicators of therapeutic response (284)

Rom J Endocrinol