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Upon depolarization of astrocytes, molecules such as AQP4 that normally localize in endfoot membranes are redistributed to non-endfoot membranes, thereby compromising AQP4 function 24

These drugs also lower postprandial TGs and apoB48 in humans (5, 14, 15) and in mice through mechanisms requiring the GLP-1R (9)

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For example, the transcription factor Nrf2 binds to the antioxidant response element in the promoter region of SLC7A11 and then upregulates its expression [33]