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Chronic inflammation can also worsen symptoms associated with autoimmune conditions, such as rheumatoid arthritis and inflammatory bowel disease ( Ginger and turmeric have powerful anti-inflammatory properties, which could help decrease pain and protect against disease

In vitro studies have demonstrated copper-dependent effects on superoxide dismutase (SOD) activity and anti-inflammatory cytokine expression

These examples clearly indicate that the activation of STAT3 signaling is able to trigger cellular senescence, probably in co-operation with NF-B and SMAD3 signaling