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The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

Through programmable biodistribution, physiological adaptability, and AI-driven design, these next-generation systems hold promise for overcoming the limitations of static treatment paradigms and delivering precision therapeutics with enduring impact

Suppression of Glucagon (-cells and -cells) GLP-1 RAs lower blood glucose by inhibiting the secretion of glucagon from pancreatic -cells, reducing hepatic glucose production

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In contrast, patients with chronic kidney disease or heart failure frequently benefit more from SGLT2 inhibitors