Leur taux peut augmenter la faveur dune exposition des nuisances environnementales telles que la fume de cigarette, la pollution atmosphrique, les polluants chimiques, les radiations UV ou lalimentation
Nevertheless, oxidative stress and H 2 O 2 were described to activate multiple stress-sensitive Ser/Thr kinases such as JNK, ERK1, and IKKb (inhibitor of NF- B), and p70S6k, which take part in insulin resistance by phosphorylation of IRS1 in serine instead of tyrosine residue, blocking insulin signaling [41]
Front Mol Biosci 9:901565 Kuang F, Liu J, Tang D, Kang R (2020) Oxidative damage and antioxidant defense in ferroptosis
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