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Weight-bearing exercise, adequate nutrition, fall prevention strategies, and regular monitoring remain the cornerstones of any bone health program

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While COP1 can function independently, it can also be incorporated into CULLIN4-RING ubiquitin ligase (CRL4) complexes through the DET1 adaptor protein

Three to 5 mice were housed in each cage under the following control conditions: a stable temperature of 251C, a 12-h light/12-h dark cycle, and the availability of food and water

This article will explore how ferroptosis impacts various pathological processes in OA, aiming to provide new insights into its prevention and treatment (Figure 2)