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In terms of next steps, the company will meet with the FDA to discuss the future development of VK2735

For example, BIM-28163, which is a ghrelin analog with full competitive GHS-R1a antagonist characteristics, stops ghrelin-stimulated growth hormone release in rats but stimulates food intake and weight gain

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4.7 Appetite and satiety Appetite and weight regulation are controlled by the central nervous system in a fairly complex manner, with the human brain playing a central role in integrating internal and external inputs and regulating energy homeostasis (Farr et al., 2016a)

Therefore, the addition of a GLP-1RA may lead to a higher risk for GI

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