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Selective GHRP for clean growth hormone axis research

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Lands LC et al

doi: 10.3389/fcell.2021.663535 Received 03 February 2021 Accepted 15 April 2021 Published 13 May 2021 Volume 9 - 2021 Edited by Zhi-Gang Zhang, Shanghai Jiao Tong University, China Reviewed by Rupali Das, Michigan State University, United States

Here, we found that the neuronal conditional-knockout (KO) of glutamyl-cysteine-ligase catalytic-subunit (GCLC), a rate-limiting enzyme for glutathione synthesis, induced brain atrophy accompanied by neuronal loss and neuroinflammation

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