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Emerson, M

The molecular mechanism of GPCR desensitization has been most extensively characterized by employing 2 AR as a model, and arrestin-mediated physical uncoupling between receptors and G proteins has been established as the fundamental mechanism of GPCR desensitization

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The mechanism is that MT entering the cell interacts with components of various signaling pathways or directly regulates their transcription levels

Time-series proteomic study of the response of hk-2 cells to hyperglycemic, hypoxic diabetic-like milieu

25,26,27,28,29 With the continuous deepening of research on lactylation, it is expected to serve as a biomarker for the early diagnosis and prognosis of diseases, and targeted lactylation is expected to become a potential strategy for disease diagnosis and treatment