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This led to the discovery that concomitant oral consumption of grapefruit juice and felodipine (a CYP3A4 substrate) can cause a several fold increase in the plasma levels of felodipine, due to enhanced bioavailability

Therefore, GGC may attenuate oligomeric A 40 -mediated disruption of endogenous antioxidant enzymes and replenish GSH levels in human brain cells

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