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(3) PUFAs in Membranes: Polyunsaturated fatty acids (PUFAs) on cell membranes are oxidized and destroyed during ferroptosis, leading to loss of cell membrane integrity and cell death

This may be related to its potential to decrease the burden of senescent cells

Antimicrob Agents Chemother 53:50465054 Acknowledgements This work was supported by the National Natural Science Foundation of China (32072916, 32302928)

Auranofin has demonstrated the capability to induce oxidative stress and apoptosis by hampering TXNRD activity in lung and breast cancer cells [233, 234]

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