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In additional analyses that used an alternative as-treated definition for drug use, the mean follow-up time among patients who started GLP1 receptor agonists was 1.8 years in the analysis with 90 day gap and tail periods, 2.6 years in the analysis with one year gap and tail periods, and 2.9 years in the analysis with two year gap and tail periods

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Although IL18 is a common ligand for IL18R1, in this study, IL18R1 could also be bound by CXCL10

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This holistic approach can enhance the effectiveness of the treatment and potentially provide better value for the investment

Individual responses depend on genetic factors