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The animal data showing GH/IGF-1 elevation and bone/lean mass gains comes from aged, often GH-deficient animal models populations with impaired baseline GH axis function

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This dual functionality establishes it as a complex yet promising target for cancer treatment (216)

With advancements in genomics and proteomics, we anticipate even more targeted applications and deeper insights into their mechanisms by the close of 2026 and beyond

Melov S, Ravenscroft J, Malik S, Gill MS, Walker DW, et al: Extension of life-span with superoxide dismutase = catalase mimetics

Pathophysiology and diagnostic value of urinary trypsin inhibitors