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Patient safety is of utmost importance to Novo Nordisk, she said
8F and G, respectively) revealed mild tissue injury with few vacuolar degenerations
counsel on vomiting-related missed doses | | Levothyroxine | Cmax reduced ~16% | Recheck TSH at 6 to 8 weeks | | Digoxin | Tmax delayed 2.5 hours, Cmax reduced 17% | Check trough level at 5 to 7 days | | Metformin | Cmax reduced 9%, AUC unchanged | No adjustment | | Statins | Cmax reduced up to 38%, AUC unchanged | No adjustment | | ACE inhibitors/ARBs | Cmax reduced ~15%, AUC unchanged | No adjustment | | DPP-4 inhibitors | Pharmacologic redundancy | Discontinue DPP-4i | | SGLT2 inhibitors | Additive efficacy, no PK interaction | No adjustment | | DOACs | No data
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Geographically, trials were concentrated in the United States, China, and Denmark, with relatively few international multicenter studies
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