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Tirzepatide treatment suppressed miR-34a, while upregulating miR-212 and miR-29c, both of which support anti-apoptotic and pro-differentiation signaling pathways

I2 = 0.0%, p = 0.436)

Appropriate medical supervision is necessary when using this medication

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The functional impact of this adduct including potential effects on binding to GIP and GLP-1 receptors, altered pharmacokinetics (ADME), and long-term safety is unknown, underscoring why rigorous identity and impurity characterization by LC-MS/MS and NMR is essential for any tirzepatide product