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It found a lack of clinical and nonclinical safety information, and was "particularly concerned" about the absence of any human data by any route, including no data to assess immunogenicity or aggregation

The dynamic range () for the maximum change of the fluorescence ratio between the fully oxidized and fully reduced state of the chromophore was calculated from the fluorescence excitation at the wavelengths used for ratiometric imaging (i.e., 405 and 488 nm)

In fact, CD33 is not relevant only for hematologic malignancies

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In an in vitro lipopolysaccharide-induced microglial activation model, sevoflurane reduced microglial activation by suppressing NF-B and MAPK signaling [30]

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