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Agmatine, a metabolite derived from L-arginine and an endogenous polyamine, is primarily produced by the metabolism of intestinal flora such as Escherichia , Bacteroides , and Enterobacteriaceae [58]

The administration of metformin and chloroquine increased the efficacy of cytarabine in suppressing NALM-6 cells, leading to decreased colony formation, increased apoptosis, and G1 phase cell cycle arrest

This D-retro-inverso peptide specifically disrupts the FOXO4-p53 protein interaction that maintains senescent cell viability, providing researchers with a sophisticated tool for investigating cellular senescence biology and its role in aging processes

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