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While these effects are generally manageable, they represent more pronounced GI side effects than observed with AOD-9604
The first is delayed gastric emptying
In comments on the CY 2025 PFS proposed rule and summarized in the CY 2025 PFS final rule (89 FR 98293), many interested parties recommended that CMS collect additional data elements, such as the NDC, stating that the NDC would help CMS better match ( the data submitted by the covered entity to the PDE data for Part D rebatable drugs dispensed during an applicable period
[5], [6] DSIP has been shown to restrict stress-induced changes in mitochondrial monoamine oxidase type A (MAO-A) and serotonin levels
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