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It also shows the oxygen consumption rate at time zero (% ROCRto) and the total oxygen consumption capacity (% TOCC) of the different antioxidants compared to those of sulfur dioxide at the usual doses

& Kuppusamy, P

N Engl J Med 312(3):137141

A pivotal RCT in 116 cannabis-dependent adolescents found that NAC (1,200 mg twice daily) more than doubled the odds of a negative urine cannabinoid test compared to placebo (OR 2.4, 95% CI 1.1-5.2) (Gray et al., Am J Psychiatry, 2012) [76]

Additionally, several drugs can be involved, such as thiazide and loop diuretics (which increase urinary excretion) and antiacid drugs (PPIs, H2 receptor blockers)

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