In aged skeletal muscle models, NNMT inhibitor treatment increased proliferating/active muscle stem cells by 60-75% following injury, myofiber cross-sectional area increased 1.8-fold at one week post-injury with high-dose treatment, and peak torque of injured muscle increased by 67% compared to control (p = 0.033), with no untoward systemic toxicity observed in plasma chemistry markers (Neelakantan et al., 2019)
It produces the most consistent results, allows precise dose titration, and matches the route used in nearly all preclinical research
Transferring the lozenge from one side of the mouth to the other to prevent the onset of soreness can minimize these incidents
So we're assuming it's small enough
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