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If you have Wilson's disease, are pregnant or breastfeeding, have active cancer, or have demonstrated copper allergy, avoidance is the prudent choice

There is no clinically validated human dosing protocol

This hormone plays a key role in regulating appetite, insulin response, and digestion

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At baseline and at weeks 8 and 12, a clinician should assess fasting insulin and HOMA-IR (the homeostasis model assessment of insulin resistance, a calculated index derived from fasting glucose and insulin), HbA1c, high-sensitivity C-reactive protein as an inflammatory marker, and body composition by DEXA scan or bioelectrical impedance

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