Some common side effects include nausea, vomiting, diarrhea, and constipation
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Additionally, the LEADER study reported a post-hoc analysis in patients with polyvascular disease (defined as atherosclerosis in two or more of the following vasculature territories: ocular, coronary arteries, cerebral arteries or arteries peripheral), in which they did not observe significant differences in the risk of non-fatal stroke in the liraglutide group versus placebo [63]
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Retatrutide raises resting heart rate by about 5-10 bpm