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The nanosystem can release DOX by the low pH endosomes while up-taken by MDR/breast cancer cells and could silence the MDR1 gene and erythroblastosis virus E26 oncogene homolog 1 gene by MBs hybridizing with target sequences, plus it is capable of hindering DOX efflux transporter of P-glycoprotein expression and causing the progression of MDR breast cancer to desist

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The resulting number is the safe sustained C rating you can realistically pull from the battery

Expression of this mutated gene greatly reduces expression and operation of astrocytic glutamate transporters, thus leading to an excitotoxicity linked to psychosocial abnormalities and impaired cognition

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Front Immunol (2022) 13:772446