These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance
The standard NHS protocol for B12 deficiency typically involves hydroxocobalamin 1mg intramuscularly three times a week for two weeks (if there's no neurological involvement) or on alternate days until no further improvement (if neurological symptoms are present)
"Structure and Function of Hormones: Growth Hormone"
When you're deficient, the symptoms are usually gradual: fatigue, brain fog, low mood, tingling in hands or feet, unexplained weakness
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While B12 can help with energy and metabolism, visible weight loss usually depends on your full program, including diet and activity