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Some mild uneasiness may occur, but it improves as your stomach gets used to it

Willis, Pathology of Tumours (Butterworth & Co., London, 1960) K

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The administration starts with a low 2.5 mg dose for the first four weeks

Most research supports 1 to 3 grams daily in divided doses taken with meals

From a strict clinical perspective, you must follow a gradual dose-escalation schedule (starting from 0.25mg) to build proper digestive tolerance before safely using this advanced dose tier