680,681,682 Small molecules targeting ferroptosis by regulating the ACSL4-LOX axis Lipid peroxidation is a hallmark of ferroptosis, and lipid-metabolizing enzymes such as ACSL4 and LOX contribute to ferroptosis
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SAD patients showed enrichment of novel genera Anaeromassilibacillus and Gordonibacter , whereas Anaeromassilibacillus was linked to autism spectrum disordera condition with high SAD comorbidity ( 3.3.4 MGBA alterations and pathophysiological mechanisms in anxiety Rodent models of anxiety disorders provide causal evidence that stress exposure disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance (Tyagi et al., 2025) and humid heat environment stress models (Weng et al., 2024) Enrichment of the phylum Proteobacteria was observed across multiple stress paradigms (Jia et al., 2024
Ghio AJ, Roggli VL, Kennedy TP, Piantadosi CA
