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SCFAs inhibit pro-inflammatory cytokine (IL-6, IL-12) release from DCs via GPR109A and HDAC suppression, skewing T cell differentiation toward tolerance ( 6 Gut microbiota mechanisms in allergic asthma We delineate the multifaceted role of gut microbiota in allergic asthma pathophysiology, highlighting microbial-immune interactions as a therapeutic frontier for airway hyperreactivity, remodeling, and allergenic sensitization as shown in Figure 2
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Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-Hydroxy-2-Nonenal
In the HG-3 and MEC-1 cell lines, after the normalizing radioactivity (in disintegrations per minute) to the cell counts, we did not observe any decreases in thymidine or uridine incorporation after 72 hours of incubation with CB-839 at any dose
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