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The absorption gap: Oral glutathione must survive stomach acid, intestinal enzymes, and first-pass liver metabolism before entering systemic circulation
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Dose-ranging studies are essential to determine optimal dosing regimens for different applications
Gastroenterology 126 : 16201633 Bibiloni R et al
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But it is known that prolonged exposure to oxidative stress can damage cellular components (proteins, lipids and DNA) [13], contribute to cellular aging [14], and play an important role in the pathogenesis of cancer, atherosclerosis, Parkinson, Alzheimers and various chronic diseases such as diabetes mellitus and its complications [15, 16, 17, 18, 19, 20]
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